When we think of bipolar disorder, we often focus on the emotional highs and lows—the extreme shifts between mania and depression that make everyday life unpredictable. But what many people don’t realize is that bipolar disorder doesn’t just affect the mind—it has a profound impact on physical health, especially heart health.
Recent research suggests that individuals with bipolar disorder face a significantly higher risk of cardiovascular disease compared to the general population. This means that, beyond managing mood swings, those with bipolar disorder also need to be aware of how their condition affects their heart. Unfortunately, this connection is rarely discussed, leaving many unaware of the risks they face.
So, why does bipolar disorder increase the risk of heart disease, and what can be done to protect both mental and physical health? Let’s break it down.

The Link Between Bipolar Disorder and Cardiovascular Disease

According to multiple studies, people with bipolar disorder are at a higher risk of developing heart problems at an earlier age than those without the condition. Some of the most common cardiovascular issues include:
• High blood pressure (hypertension)
• High cholesterol levels
• Obesity
• Diabetesi
• Heart attacks and strokes
But why does this happen? The connection isn’t just a coincidence—it’s a result of multiple biological, lifestyle, and medication-related factors that come with bipolar disorder.
Why People with Bipolar Disorder Face Higher Heart Risks
1. Chronic Stress and Inflammation
Living with bipolar disorder means constantly navigating emotional extremes, which can put significant stress on the body. When you’re in a manic episode, your body is in overdrive—your heart races, your blood pressure spikes, and stress hormones like cortisol and adrenaline flood your system.
2. Medication Side Effects
Many people with bipolar disorder rely on mood stabilizers, antipsychotics, and antidepressants to manage their condition. While these medications are crucial for mental stability, some of them increase the risk of weight gain, high cholesterol, and insulin resistance—all of which contribute to heart disease.
For example:
• Atypical antipsychotics (such as olanzapine and quetiapine) can lead to significant weight gain and metabolic issues.
• Mood stabilizers (like lithium and valproate) may contribute to thyroid problems and weight fluctuations.
• Some antidepressants can affect heart rhythm and blood pressure.
This makes regular health check-ups essential for anyone on long-term medication.
3. Lifestyle Factors: Sleep, Diet, and Exercise
Bipolar disorder disrupts sleep patterns, leading to chronic sleep deprivation. Lack of sleep has been directly linked to an increased risk of heart disease, high blood pressure, and obesity.
Manic episodes might push someone to be overly active—sometimes even exercising excessively—while depressive episodes often lead to sedentary behavior and unhealthy eating habits. The combination of irregular physical activity, emotional eating, and poor diet choices can accelerate cardiovascular problems.
4. Substance Use and Smoking
People with bipolar disorder are more likely to smoke, drink alcohol, or use drugs as a way to self-medicate. Unfortunately, these habits dramatically increase heart disease risk.
• Nicotine constricts blood vessels, raising blood pressure and increasing the risk of strokes and heart attacks.
• Alcohol and recreational drugs can cause irregular heart rhythms and long-term heart damage.
Addressing addiction and substance use is a critical part of reducing cardiovascular risk.
5. Genetic and Biological Factors
Some researchers believe that bipolar disorder and cardiovascular disease may share genetic links. Certain genes that contribute to mood regulation might also play a role in heart health. Additionally, people with bipolar disorder tend to have higher levels of inflammatory markers, which can damage the cardiovascular system over time.
How to Protect Heart Health While Managing Bipolar Disorder
The good news? You can take steps to protect your heart while managing bipolar disorder. Here’s how:
1. Regular Health Check-ups
• Get routine blood pressure, cholesterol, and blood sugar tests.
• Work closely with your doctor to monitor medication side effects and adjust dosages if necessary.
2. Prioritize Heart-Healthy Habits
• Exercise regularly – Even moderate activity (like walking or yoga) can significantly reduce cardiovascular risk.
• Eat a balanced diet – Focus on whole grains, lean proteins, healthy fats, and plenty of fruits and vegetables.
• Stay hydrated and avoid excess caffeine or sugar, which can trigger mood swings and affect heart health.
3. Manage Stress and Sleep
• Practice stress-reducing activities like meditation, deep breathing, or therapy.
• Stick to a consistent sleep schedule to stabilise mood and support heart health.
• Avoid screen time before bed and create a relaxing bedtime routine.
4. Quit Smoking and Limit Alcohol
• If you smoke, consider quitting—it’s one of the best things you can do for both your mental and physical health.
• Limit alcohol intake to prevent worsening of both mood symptoms and heart problems.
5. Seek Emotional Support
• Join a support group for people with bipolar disorder.
• Talk to a therapist or counselor who understands both mental health and physical health challenges.
• Educate family and friends about the connection between bipolar disorder and heart health so they can support you better.
Final Thoughts: A Holistic Approach to Bipolar Disorder
Bipolar disorder isn’t just about mental health—it’s a condition that affects the whole body, including the heart. While the emotional highs and lows can be overwhelming, it’s crucial to remember that physical health needs attention too.
If you or someone you love has bipolar disorder, taking proactive steps to protect the heart can improve overall well-being and quality of life. Simple lifestyle changes, regular medical check-ups, and emotional support can make a huge difference.
Your heart and mind are deeply connected—taking care of both is the key to a healthier, more balanced life.